On July 6, 1885, the rabies vaccine developed by Louis Pasteur began to be adopted internationally, including in the United States shortly after, marking a turning point in public health responses to the disease. American physicians followed developments closely and soon used the treatment for exposed patients.

Before vaccines, rabies was almost always fatal once symptoms appeared. The new method offered hope and led to efforts to control rabies in animals as well. The spread of vaccination clinics reduced deaths and improved confidence in scientific medicine. This moment helped usher in the modern era of preventive medicine in the U.S.