1. For how many days did Agatha Christie famously disappear in 1926?

2. Who was the real-life medical professor who inspired the character of Sherlock Holmes?

3. In what year did Toni Morrison become the first African American woman to win the Nobel Prize in Literature?

4. What unique literary style did Langston Hughes pioneer by incorporating the rhythms of music into his verse?

5. To which city did James Baldwin move in 1948 to find the freedom to write his debut novel?

6. Why did Anthony Burgess want 'A Clockwork Orange' to have exactly 21 chapters?

7. What real-world event forced Mary Shelley to stay indoors and write 'Frankenstein'?

8. What scientific concept does Pointillism rely on to create secondary colors?

9. Hieronymus Bosch's famous work is a 'triptych.' What does this term mean?

10. Who was the first woman to win the Pulitzer Prize for Fiction in 1921?

11. Why did Picasso choose to paint 'Guernica' using only black, white, and grey?

12. Why was Zora Neale Hurston's 'Barracoon' rejected by publishers for nearly 90 years?

13. In Dutch Golden Age art, what is the term for a painting of an exaggerated facial expression or exotic character?

14. What binding agent did Jan van Eyck use to perfect the medium of oil paint?

15. Which famous Romantic poet was the father of Ada Lovelace?

16. Which mournful refrain did Poe choose as the central word for his poem 'The Raven'?

17. What linguistic tool did oral poets use to memorize the thousands of lines in the Odyssey?

18. What was Antoni Gaudí's primary inspiration for the architectural shapes within the Sagrada Família?

19. What military communication system served as the inspiration for Louis Braille's reading system?

20. Why was Rembrandt's 'The Night Watch' mistakenly thought to take place at night for hundreds of years?