1. Who discovered penicillin in 1928?

2. Who painted the ceiling of the Sistine Chapel?

3. Cleopatra was a member of which Greek-origin dynasty that ruled Egypt?

4. Leonardo da Vinci’s technique of 'sfumato' is best described as what?

5. Catherine the Great belonged to which famous Russian imperial dynasty?

6. Mansa Musa was the ruler of which wealthy West African empire?

7. On which island was Nelson Mandela imprisoned for 18 of his 27 years in jail?

8. Saladin famously fought against which English King during the Third Crusade?

9. Which U.S. President did Frederick Douglass advise during the Civil War?

10. What is the name of the collection of sayings and ideas attributed to Confucius?

11. What artifact is often cited as the first declaration of human rights issued by Cyrus the Great?

12. What was the title of Sojourner Truth's famous 1851 speech in Akron, Ohio?

13. Wu Zetian was a major patron of which religion, often using it to justify her rule?

14. Rosa Luxemburg was a co-founder of which revolutionary group in Germany?

15. What was the name of the German cipher machine that Turing's team cracked?

16. What was the name of the conflict led by Spartacus against Rome?

17. Which major modern-day city was destroyed by Boudica's army in 60 AD?

18. Catherine the Great's vast art collection became the foundation of which famous world museum?

19. What concept did Ibn Khaldun develop to describe the social bond that holds a community together?

20. Which pesticide was famously targeted for its environmental impact in Rachel Carson's 'Silent Spring'?